As the English Premier League returns after the international break, several clubs are battling a wave of injuries that could shape their performances in the coming fixtures.
From heavyweights like Arsenal, Manchester City, and Liverpool, to mid-table sides trying to steady their season, nearly every team has a key player missing due to fitness concerns.
The Premier League’s latest medical update on Friday revealed a long list of players nursing knee, hamstring, and groin issues — some of whom may face weeks or even months on the sidelines. This leaves managers with difficult selection choices ahead of a decisive match week that could affect both ends of the table.
Injury List by Club (as of Friday, October 17, 2025)
Arsenal
- Gabriel Jesus – Knee
- Kai Havertz – Knee
- Noni Madueke – Knee
- Piero Hincapié – Groin
- Martin Ødegaard – Knee
Aston Villa
- Youri Tielemans – Calf
- Tyrone Mings – Knock
- Jadon Sancho – Illness
- Ollie Watkins – Knock
Bournemouth
- Enes Ünal – Knee
- Adam Smith – Hamstring
- David Brooks – Hamstring
Burnley
- Lyle Foster – Dead leg
- Jaidon Anthony – Knock
- Connor Roberts – Knock
- Jordan Beyer – Knee
- Zeki Amdouni – Knee
Brentford
- Gustavo Nunes – Hamstring
- Edmond-Paris Maghoma – Hamstring
- Yehor Yarmoliuk – Knock
- Antoni Milambo – Knee
Brighton & Hove Albion
- Adam Webster – Knee
- Solly March – Knee
- Jack Hinshelwood – Ankle
- Joel Veltman – Calf
- Kaoru Mitoma – Ankle
- Brajan Gruda – Muscle
Chelsea
- Levi Colwill – Knee
- Liam Delap – Hamstring
- Dario Essugo – Thigh
- Cole Palmer – Groin
- Moisés Caicedo – Knock
- Enzo Fernández – Knock
- Pedro Neto – Knock
- Benoît Badiashile – Knock
Crystal Palace
- Chadi Riad – Knee
- Cheick Doucouré – Knee
- Caleb Kporha – Back
Everton
- Jarrad Branthwaite – Hamstring
- Merlin Röhl – Hip
Fulham
- Kenny Tete – Knee
- Raúl Jiménez – Knock
- Rodrigo Muniz – Muscle
- Saša Lukić – Groin
Leeds United
- Lucas Perri – Thigh
- Wilfried Gnonto – Calf
- Daniel James – Ankle
- Harry Gray – Hip
Liverpool
- Giovanni Leoni – Knee
- Stefan Bajčetić – Hamstring
- Jayden Danns – Hamstring
- Federico Chiesa – Knock
- Ibrahima Konaté – Quadriceps
Manchester City
- Rayan Aït-Nouri – Knock
- Omar Marmoush – Knee
- Mateo Kovačić – Achilles
Manchester United
- Lisandro Martínez – Knee
- Noussair Mazraoui – Knock
Newcastle United
- Jacob Ramsey – Ankle
- Joelinton – Knee
- Yoane Wissa – Knee
- Tino Livramento – Knee
- Lewis Hall – Thigh
Nottingham Forest
- Ola Aina – Hamstring
- Douglas Luiz – Hamstring
- Oleksandr Zinchenko – Groin
Sunderland
- Aji Alese – Shoulder
- Dennis Cirkin – Wrist
- Leo Fuhr Hjelde – Achilles
- Romaine Mundle – Hamstring
- Habib Diarra – Groin
- Omar Alderete – Knock
- Noah Sadiki – Knock
Tottenham Hotspur
- Dejan Kulusevski – Knee
- James Maddison – Knee
- Radu Drăgușin – Knee
- Kota Takai – Foot
- Yves Bissouma – Knock
- Dominic Solanke – Ankle
West Ham United
- George Earthy – Hamstring
Wolverhampton Wanderers
- Matt Doherty – Wrist
- Leon Chiwome – Knee
- Toti Gomes – Illness
Clubs such as Arsenal, Chelsea, and Brighton are among the hardest hit, each dealing with multiple knee and muscle-related injuries that could disrupt their squad rotation across domestic and European competitions.
For Arsenal, the absence of Gabriel Jesus and Kai Havertz could weaken their attacking edge, while Manchester City will be without Mateo Kovačić, whose composure and control in midfield are difficult to replace.
With the season entering a crucial phase, teams will need to dig deep — relying on squad depth and tactical adaptability — to stay competitive amid this injury crisis.
